|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Double-stranded RNA-binding protein Staufen homolog 1, STAU1, STAU|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||STAU1 / Staufen Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.|
|Cellular Location||Cytoplasm. Rough endoplasmic reticulum Note=Localizes exclusively with the rough reticulum endoplasmic (RER)|
|Tissue Location||Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta|
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Provided below are standard protocols that you may find useful for product applications.
Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
Wickham L.,et al.Mol. Cell. Biol. 19:2220-2230(1999).
Falcon A.M.,et al.Nucleic Acids Res. 27:2241-2247(1999).
Mao Y.,et al.Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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