TCF12 / HEB Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, ICC, E |
---|---|
Primary Accession | Q99081 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 73kDa |
Dilution | IHC-P (5 µg/ml), WB (0.5-1 µg/ml), |
Gene ID | 6938 |
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Other Names | Transcription factor 12, TCF-12, Class B basic helix-loop-helix protein 20, bHLHb20, DNA-binding protein HTF4, E-box-binding protein, Transcription factor HTF-4, TCF12, BHLHB20, HEB, HTF4 |
Target/Specificity | Human TCF12 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | TCF12 / HEB Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TCF12 |
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Synonyms | BHLHB20, HEB, HTF4 |
Function | Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3') (By similarity). May be involved in the functional network that regulates the development of the GnRH axis (PubMed:32620954). |
Cellular Location | Nucleus. |
Tissue Location | Expressed in several tissues and cell types including skeletal muscle, thymus, and a B-cell line |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
References
Zhang Y.,et al.DNA Seq. 2:397-403(1992).
Hu J.S.,et al.Mol. Cell. Biol. 12:1031-1042(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Zody M.C.,et al.Nature 440:671-675(2006).
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