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>   home   >   Products   >   Primary Antibodies   >   ATF1 Antibody (clone 3E7)   

ATF1 Antibody (clone 3E7)

Mouse Monoclonal Antibody

     
  • WB - ATF1 Antibody (clone 3E7) ALS14022
    Western blot of ATF1 expression in transfected 293T cell line by ATF1 monoclonal antibody (M03),...
  • IHC - ATF1 Antibody (clone 3E7) ALS14022
    Anti-ATF1 antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P18846
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3E7
Calculated MW 29kDa
Dilution IHC-P (2.5 µg/ml)
Additional Information
Gene ID 466
Other Names Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, Protein TREB36, ATF1
Target/Specificity Human ATF1
Reconstitution & Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsATF1 Antibody (clone 3E7) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATF1
Function This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Cellular Location Nucleus.
Citations (0)

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Background

This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

References

Yoshimura T.,et al.EMBO J. 9:2537-2542(1990).
Rehfuss R.P.,et al.J. Biol. Chem. 266:18431-18434(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Hai T.,et al.Genes Dev. 3:2083-2090(1989).

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$ 450.00
Cat# ALS14022
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