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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CD58 Antibody (clone 2D11-B10)   

CD58 Antibody (clone 2D11-B10)

Mouse Monoclonal Antibody

     
  • WB - CD58 Antibody (clone 2D11-B10) ALS14030
    CD58 monoclonal antibody (M01), clone 2D11-B10 Western blot of CD58 expression in Jurkat.
  • IF - CD58 Antibody (clone 2D11-B10) ALS14030
    Immunofluorescence of monoclonal antibody to CD58 on HeLa cell. [antibody concentration 10 ug/ml]
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P19256
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2D11-B10
Calculated MW 28kDa
Dilution IF (10 µg/ml), IHC-P (5 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 965
Other Names Lymphocyte function-associated antigen 3, Ag3, Surface glycoprotein LFA-3, CD58, CD58, LFA3
Target/Specificity Human CD58
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsCD58 Antibody (clone 2D11-B10) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD58
Synonyms LFA3
Function Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen- presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen- presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

References

Wallner B.P.,et al.J. Exp. Med. 166:923-932(1987).
Seed B.,et al.Nature 329:840-842(1987).
Wallich R.,et al.J. Immunol. 160:2862-2871(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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$ 450.00
Cat# ALS14030
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