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CPS1 Antibody (clone 8H8)

Mouse Monoclonal Antibody

     
  • WB - CPS1 Antibody (clone 8H8) ALS14036
    CPS1 monoclonal antibody, clone 8H8 Western blot of CPS1 expression in HeLa.
    detail
  • IHC - CPS1 Antibody (clone 8H8) ALS14036
    Anti-CPS1 antibody IHC of human liver.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P31327
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 8H8
Calculated MW 165kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 1373
Other Names Carbamoyl-phosphate synthase [ammonia], mitochondrial, 6.3.4.16, Carbamoyl-phosphate synthetase I, CPSase I, CPS1
Target/Specificity Human CPS1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsCPS1 Antibody (clone 8H8) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPS1
Function Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
Cellular Location Mitochondrion. Nucleus, nucleolus. Cell membrane {ECO:0000250|UniProtKB:Q8C196}; Peripheral membrane protein; Extracellular side {ECO:0000250|UniProtKB:Q8C196} Note=Localizes to the cell surface of hepatocytes {ECO:0000250|UniProtKB:Q8C196}
Tissue Location Primarily in the liver and small intestine.
Research Areas
Citations (0)
citation

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Background

Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.

References

Haraguchi Y.,et al.Gene 107:335-340(1991).
Finckh U.,et al.Hum. Mutat. 12:206-211(1998).
Summar M.L.,et al.Gene 311:51-57(2003).
Huo R.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Funghini S.,et al.Hum. Mutat. 22:340-341(2003).

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Discontinued
Cat# ALS14036
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