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PHB / Prohibitin Antibody (clone 3F4-2B2)

Mouse Monoclonal Antibody

     
  • WB - PHB / Prohibitin Antibody (clone 3F4-2B2) ALS14057
    PHB monoclonal antibody clone 3F4-2B2 Western blot of PHB expression in HeLa.
  • IF - PHB / Prohibitin Antibody (clone 3F4-2B2) ALS14057
    Immunofluorescence of monoclonal antibody to PHB on HeLa cell. [antibody concentration 1 ~10 ug/ml].
  • IHC - PHB / Prohibitin Antibody (clone 3F4-2B2) ALS14057
    Anti-PHB / Prohibitin antibody IHC of human kidney, tubules.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P35232
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3F4-2B2
Calculated MW 30kDa
Dilution IF (1-10 µg/ml), IHC-P (10 µg/ml),
Additional Information
Gene ID 5245
Other Names Prohibitin, PHB
Target/Specificity Human Prohibitin
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsPHB / Prohibitin Antibody (clone 3F4-2B2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHB
Function Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
Cellular Location Mitochondrion inner membrane.
Tissue Location Widely expressed in different tissues.
Research Areas
Citations (0)

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Background

Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.

References

Sato T.,et al.Cancer Res. 52:1643-1646(1992).
Sato T.,et al.Genomics 17:762-764(1993).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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$ 450.00
Cat# ALS14057
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