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PHGDH Antibody (clone 4A3-1D6)

Mouse Monoclonal Antibody

     
  • WB - PHGDH Antibody (clone 4A3-1D6) ALS14090
    Western blot of PHGDH expression in human liver with PHGDH monoclonal antibody, clone 4A3-1D6.
    detail
  • WB - PHGDH Antibody (clone 4A3-1D6) ALS14090
    Western blot of PHGDH expression in transfected 293T cell line by PHGDH monoclonal antibody,...
    detail
  • IF - PHGDH Antibody (clone 4A3-1D6) ALS14090
    Immunofluorescence of monoclonal antibody to PHGDH on HeLa cell.
    detail
  • IP - PHGDH Antibody (clone 4A3-1D6) ALS14090
    Immunoprecipitation of PHGDH transfected lysate using anti-PHGDH monoclonal antibody and Protein...
    detail
  • IHC - PHGDH Antibody (clone 4A3-1D6) ALS14090
    Anti-PHGDH antibody IHC of human pancreas.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E, IP
Primary Accession O43175
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4A3-1D6
Calculated MW 57kDa
Dilution IF (1-10 µg/ml), IHC-P (5 µg/ml),
Additional Information
Gene ID 26227
Other Names D-3-phosphoglycerate dehydrogenase, 3-PGDH, 1.1.1.95, PHGDH, PGDH3
Target/Specificity Human PHGDH
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsPHGDH Antibody (clone 4A3-1D6) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHGDH
Synonyms PGDH3
Function Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.
Research Areas
Citations (0)
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References

Cho H.M.,et al.Gene 245:193-201(2000).
Klomp L.W.J.,et al.Am. J. Hum. Genet. 67:1389-1399(2000).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).

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Discontinued
Cat# ALS14090
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