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GHRL / Ghrelin Antibody (clone 2F4)

Mouse Monoclonal Antibody

     
  • WB - GHRL / Ghrelin Antibody (clone 2F4) ALS14096
    GHRL monoclonal antibody (M01), clone 2F4. Western blot of GHRL expression in HeLa.
    detail
  • IHC - GHRL / Ghrelin Antibody (clone 2F4) ALS14096
    Anti-Ghrelin antibody IHC of human colon, epithelium.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UBU3
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2F4
Calculated MW 13kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 51738
Other Names Appetite-regulating hormone, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Protein M46, Ghrelin-27, Ghrelin-28, Ghrelin, Obestatin, GHRL, MTLRP
Target/Specificity Human GHRL
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsGHRL / Ghrelin Antibody (clone 2F4) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GHRL
Synonyms MTLRP
Function [Ghrelin-27]: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR) (PubMed:10604470). Induces the release of growth hormone from the pituitary (PubMed:10604470). Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Cellular Location Secreted.
Tissue Location Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy
Research Areas
Citations (0)
citation

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Background

Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.

References

Kojima M.,et al.Nature 402:656-660(1999).
Tomasetto C.,et al.Gastroenterology 119:395-405(2000).
Wajnrajch M.P.,et al.J. Endocr. Genet. 1:231-233(2000).
Hosoda H.,et al.J. Biol. Chem. 278:64-70(2003).
Seim I.,et al.BMC Genomics 8:298-298(2007).

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Discontinued
Cat# ALS14096
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