|Application ||WB, IHC-P, E|
|Dilution||IHC-P (5 µg/ml), WB (1:500-1:1000),|
|Other Names||Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Macrophage mannose receptor 1-like protein 1, CD206, MRC1, CLEC13D, CLEC13DL, MRC1L1|
|Reconstitution & Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||Mannose Receptor / CD206 Antibody (clone 5C11) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CLEC13D, CLEC13DL, MRC1L1|
|Function||Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.|
|Cellular Location||Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.
Taylor M.E.,et al.J. Biol. Chem. 265:12156-12162(1990).
Ezekowitz R.A.,et al.J. Exp. Med. 172:1785-1794(1990).
Kim S.J.,et al.Genomics 14:721-727(1992).
Deloukas P.,et al.Nature 429:375-381(2004).
Taylor M.E.,et al.J. Biol. Chem. 267:1719-1726(1992).
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