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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SOLO / SESTD1 Antibody (C-Terminus)   

SOLO / SESTD1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - SOLO / SESTD1 Antibody (C-Terminus) ALS14119
    Immunofluorescence of SESTD1 in Human Brain cells with SESTD1 antibody at 20 ug/ml.
  • WB - SOLO / SESTD1 Antibody (C-Terminus) ALS14119
    Western blot analysis of SESTD1 in rat brain tissue lysate with SESTD1 antibody at 1 ug/ml in...
  • IHC - SOLO / SESTD1 Antibody (C-Terminus) ALS14119
    Anti-SESTD1 antibody IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q86VW0
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 79kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 91404
Other Names SEC14 domain and spectrin repeat-containing protein 1, Huntingtin-interacting protein-like protein, Protein Solo, SESTD1, SOLO
Target/Specificity Human SESTD1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsSOLO / SESTD1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SESTD1
Synonyms SOLO
Function May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.
Tissue Location Broad expression. High expression in thalamus and brain. Significantly expressed in vasculature
Research Areas
Citations (0)

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Background

May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.

References

Xu J.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Miehe S.,et al.J. Biol. Chem. 285:12426-12434(2010).

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$ 395.00
Cat# ALS14119
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