S100A6 Antibody (clone 6B5)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | P06703 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 6B5 |
Calculated MW | 10kDa |
Dilution | IF (10 µg/ml), IHC-P (5 µg/ml), |
Gene ID | 6277 |
---|---|
Other Names | Protein S100-A6, Calcyclin, Growth factor-inducible protein 2A9, MLN 4, Prolactin receptor-associated protein, PRA, S100 calcium-binding protein A6, S100A6, CACY |
Target/Specificity | Human S100A6 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | S100A6 Antibody (clone 6B5) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | S100A6 |
---|---|
Synonyms | CACY |
Function | May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. |
Cellular Location | Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side |
Volume | 100 µl |
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Background
May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
References
Calabretta B.,et al.J. Biol. Chem. 261:12628-12632(1986).
Ferrari S.,et al.J. Biol. Chem. 262:8325-8332(1987).
Murphy L.C.,et al.J. Biol. Chem. 263:2397-2401(1988).
Wu J.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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