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TATI / SPINK1 Antibody (clone 4D4)

Mouse Monoclonal Antibody

     
  • WB - TATI / SPINK1 Antibody (clone 4D4) ALS14158
    SPINK1 monoclonal antibody clone 4D4. Western blot of SPINK1 expression in human pancreas.
  • IHC - TATI / SPINK1 Antibody (clone 4D4) ALS14158
    Anti-SPINK1 antibody IHC of human pancreas.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, IP
Primary Accession P00995
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4D4
Calculated MW 9kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 6690
Other Names Pancreatic secretory trypsin inhibitor, Serine protease inhibitor Kazal-type 1, Tumor-associated trypsin inhibitor, TATI, SPINK1, PSTI
Target/Specificity Human SPINK1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsTATI / SPINK1 Antibody (clone 4D4) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPINK1
Synonyms PSTI
Function Serine protease inhibitor which exhibits anti-trypsin activity (PubMed:7142173). In the pancreas, protects against trypsin-catalyzed premature activation of zymogens (By similarity).
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.

References

Horii A.,et al.Biochem. Biophys. Res. Commun. 149:635-641(1987).
Yamamoto T.,et al.Biochem. Biophys. Res. Commun. 132:605-612(1985).
Tomita N.,et al.FEBS Lett. 225:113-119(1987).
Witt H.,et al.Nat. Genet. 25:213-216(2000).
Bartelt D.C.,et al.Arch. Biochem. Biophys. 179:189-199(1977).

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$ 450.00
Cat# ALS14158
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