TATI / SPINK1 Antibody (clone 4D4)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E, IP |
---|---|
Primary Accession | P00995 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 4D4 |
Calculated MW | 9kDa |
Dilution | IHC-P (5 µg/ml), WB (1:500-1:1000), |
Gene ID | 6690 |
---|---|
Other Names | Pancreatic secretory trypsin inhibitor, Serine protease inhibitor Kazal-type 1, Tumor-associated trypsin inhibitor, TATI, SPINK1, PSTI |
Target/Specificity | Human SPINK1 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | TATI / SPINK1 Antibody (clone 4D4) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SPINK1 |
---|---|
Synonyms | PSTI |
Function | Serine protease inhibitor which exhibits anti-trypsin activity (PubMed:7142173). In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). |
Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.
References
Horii A.,et al.Biochem. Biophys. Res. Commun. 149:635-641(1987).
Yamamoto T.,et al.Biochem. Biophys. Res. Commun. 132:605-612(1985).
Tomita N.,et al.FEBS Lett. 225:113-119(1987).
Witt H.,et al.Nat. Genet. 25:213-216(2000).
Bartelt D.C.,et al.Arch. Biochem. Biophys. 179:189-199(1977).
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