|Application ||WB, IHC-P, IF, E|
|Dilution||IF (10 µg/ml), IHC-P (5 µg/ml),|
|Other Names||Signal transducer and activator of transcription 5B, STAT5B|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||STAT5B Antibody (clone 2D1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.|
|Cellular Location||Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.|
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Provided below are standard protocols that you may find useful for product applications.
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
Silva C.M.,et al.Mol. Endocrinol. 10:508-518(1996).
Silva C.M.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Lin J.-X.,et al.J. Biol. Chem. 271:10738-10744(1996).
Ambrosio R.,et al.Gene 285:311-318(2002).
Sawka-Verhelle D.,et al.Eur. J. Biochem. 250:411-417(1997).
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