|Clone Names||OV-TL 12/30|
|Other Names||Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7, KRT7, SCL|
|Target/Specificity||OVTL12/30 reacts specifically with Keratin 7. It stains a 54 kD protein band of cytoskeletal proteins from cell lines in one and two dimensional immunoblots.|
|Reconstitution & Storage||Store at 4°C.|
|Precautions||KRT7 / CK7 / Cytokeratin 7 Antibody (clone OV-TL 12/30) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).|
|Tissue Location||Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus|
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Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Glass C.,et al.J. Cell Biol. 101:2366-2373(1985).
Glass C.,et al.J. Cell Biol. 107:1337-1350(1988).
Kaba A.,et al.Biochimie 81:709-715(1999).
Smith F.J.D.,et al.Biochem. Biophys. Res. Commun. 297:818-827(2002).
Scherer S.E.,et al.Nature 440:346-351(2006).
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