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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CIB2 / KIP2 Antibody (aa21-70)   

CIB2 / KIP2 Antibody (aa21-70)

Rabbit Polyclonal Antibody

     
  • IHC - CIB2 / KIP2 Antibody (aa21-70) ALS14200
    Anti-CIB2 antibody IHC of human thyroid, c-cells.
  • IHC - CIB2 / KIP2 Antibody (aa21-70) ALS14200
    Anti-CIB2 antibody IHC of human adrenal medulla.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession O75838
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 22kDa
Dilution ELISA (1:5000), IHC-P (10 µg/ml),
Additional Information
Gene ID 10518
Other Names Calcium and integrin-binding family member 2, Kinase-interacting protein 2, KIP 2, CIB2, KIP2
Target/Specificity CIB2 Antibody detects endogenous levels of total CIB2 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsCIB2 / KIP2 Antibody (aa21-70) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CIB2
Synonyms KIP2
Function Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (PubMed:23023331, PubMed:26173970). May be involved in the mechanotransduction process (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q9Z309}. Cell projection, stereocilium Photoreceptor inner segment {ECO:0000250|UniProtKB:Q9Z309}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:Q9Z309}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q9Z309}. Note=Colocalized with ITGA7 at the myotendinous junctions (MTJ) and at the neuromuscular junctions (NMJ) (By similarity). Localizes in the cuticular plate along and at the tip of the stereocilia of vestibular sensory hair cells (PubMed:26173970). {ECO:0000250|UniProtKB:Q9Z309, ECO:0000269|PubMed:26173970}
Tissue Location Widely expressed (PubMed:23023331).
Volume 50 µl
Research Areas
Citations (0)

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Background

Calcium-binding protein critical for proper photoreceptor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity).

References

Seki N.,et al.Biochim. Biophys. Acta 1444:143-147(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:671-675(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Huang H.,et al.Biochem. Cell Biol. 90:646-656(2012).

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$ 395.00
Cat# ALS14200
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