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SLC6A6 / Taurine Transporter Antibody (aa561-610)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E |
|---|---|
| Primary Accession | P31641 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 70kDa |
| Dilution | ELISA (1:10000), IHC-P (5 µg/ml), |
| Gene ID | 6533 |
|---|---|
| Other Names | Sodium- and chloride-dependent taurine transporter, Solute carrier family 6 member 6, SLC6A6 |
| Target/Specificity | SLC6A6 Antibody detects endogenous levels of total SLC6A6 protein. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | SLC6A6 / Taurine Transporter Antibody (aa561-610) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC6A6 |
|---|---|
| Function | Mediates sodium- and chloride-dependent transport of taurine (PubMed:8382624, PubMed:8010975, PubMed:8654117, PubMed:31345061, PubMed:31903486). Mediates transport of beta-alanine (PubMed:8010975). Can also mediate transport of hypotaurine and gamma-aminobutyric acid (GABA) (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.
References
Jhiang S.M.,et al.FEBS Lett. 318:139-144(1993).
Ramamoorthy S.,et al.Biochem. J. 300:893-900(1994).
Miyamoto Y.,et al.Curr. Eye Res. 15:345-349(1996).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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