TNNC1 / Cardiac Troponin C Antibody
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | P63316 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 18kDa |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 7134 |
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Other Names | Troponin C, slow skeletal and cardiac muscles, TN-C, TNNC1, TNNC |
Target/Specificity | Recognizes human cardiac Troponin C: 100%. |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | TNNC1 / Cardiac Troponin C Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TNNC1 |
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Synonyms | TNNC |
Function | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
References
Roher A.,et al.Muscle Nerve 9:73-77(1986).
Gahlmann R.,et al.J. Mol. Biol. 201:379-391(1988).
Schreier T.,et al.J. Biol. Chem. 265:21247-21253(1990).
Margossian S.S.,et al.Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases.
Spyracopoulos L.,et al.Biochemistry 36:12138-12146(1997).
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