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NRGN / Neurogranin Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - NRGN / Neurogranin Antibody (Internal) ALS14257
    NRGN antibody (0.1 ug/ml) staining of Mouse Brain lysate (35 ug protein/ml in RIPA buffer).
    detail
  • IHC - NRGN / Neurogranin Antibody (Internal) ALS14257
    Anti-NRGN / Neurogranin antibody IHC of human brain, cortex.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q92686
Reactivity Human, Mouse, Rabbit, Pig, Goat, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 8kDa
Dilution ELISA (1:8000), IHC-P (3.75 µg/ml), WB (0.1-0.3 µg/ml)
Additional Information
Gene ID 4900
Other Names Neurogranin, Ng, RC3, NEUG(55-78), NRGN
Target/Specificity Human NRGN / Neurogranin. Reported variants represent identical protein: NP_006167.1, NP_001119653.1
Reconstitution & Storage Long term: -70°C; Short term: -20°C; Avoid freeze-thaw cycles.
PrecautionsNRGN / Neurogranin Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRGN
Function Acts as a 'third messenger' substrate of protein kinase C- mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity).
Tissue Location In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease.
Research Areas
Citations (0)
citation

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Background

Acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity).

References

Mertsalov I.B.,et al.Bioorg. Khim. 22:366-369(1996).
Mertsalov I.B.,et al.Bioorg. Khim. 23:961-968(1997).
Martinez de Arrieta C.,et al.Genomics 41:243-249(1997).
Chang J.W.,et al.J. Neuropathol. Exp. Neurol. 56:1105-1118(1997).
Mertsalov I.B.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS14257
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