|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (1:200), WB (1:2000),|
|Other Names||Mitochondrial peptide methionine sulfoxide reductase, 188.8.131.52, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase, Protein-methionine-S-oxide reductase, PMSR, MSRA|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||MSRA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.|
|Cellular Location||Isoform 1: Mitochondrion. Isoform 3: Cytoplasm. Nucleus.|
|Tissue Location||Ubiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus|
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Provided below are standard protocols that you may find useful for product applications.
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Kuschel L.,et al.FEBS Lett. 456:17-21(1999).
Hansel A.,et al.Biochim. Biophys. Acta 1703:239-247(2005).
Lee J.W.,et al.Exp. Eye Res. 82:816-827(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zhao Y.,et al.Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
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