|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Dilution||ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.2-0.5 µg/ml)|
|Other Names||Transforming growth factor-beta-induced protein ig-h3, Beta ig-h3, Kerato-epithelin, RGD-containing collagen-associated protein, RGD-CAP, TGFBI, BIGH3|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||TGFBI Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in cell adhesion (PubMed:8024701). May play a role in cell-collagen interactions (By similarity).|
|Cellular Location||Secreted Secreted, extracellular space, extracellular matrix. Note=May be associated both with microfibrils and with the cell surface (PubMed:8077289)|
|Tissue Location||Highly expressed in the corneal epithelium (PubMed:8077289). Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas (PubMed:8077289)|
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Provided below are standard protocols that you may find useful for product applications.
Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.
Skonier J.,et al.DNA Cell Biol. 11:511-522(1992).
Munier F.L.,et al.Nat. Genet. 15:247-251(1997).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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