|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:5000-1:40000), IHC-P (5 µg/ml), WB (1:5000-1:40000)|
|Other Names||Apolipoprotein E, Apo-E, APOE|
|Target/Specificity||Apo E recombinant protein|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.|
|Precautions||APOE / Apolipoprotein E Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.|
|Tissue Location||Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
Zannis V.I.,et al.J. Biol. Chem. 259:5495-5499(1984).
McLean J.W.,et al.J. Biol. Chem. 259:6498-6504(1984).
Paik Y.-K.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:3445-3449(1985).
Emi M.,et al.Genomics 3:373-379(1988).
Freitas E.M.,et al.DNA Seq. 9:89-100(1998).
If you have any additional inquiries please email technical services at email@example.com.