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KRT20 / CK20 / Cytokeratin 20 Antibody (clone IT-Ks 20.10, FITC)

Mouse Monoclonal Antibody

     
  • IHC - KRT20 / CK20 / Cytokeratin 20 Antibody (clone IT-Ks 20.10, FITC) ALS14286
    Anti-KRT20 / Cytokeratin 20 antibody IHC of human small intestine.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, Flo
Primary Accession P35900
Reactivity Human, Rat, Pig
Host Mouse
Clonality Monoclonal
Clone Names IT-Ks 20.10
Calculated MW 48kDa
Dilution IHC-P (1:50)
Additional Information
Gene ID 54474
Other Names Keratin, type I cytoskeletal 20, Cytokeratin-20, CK-20, Keratin-20, K20, Protein IT, KRT20
Target/Specificity Human, pig, and rat. Polypeptide reacting: Protein IT Reactivities on cultured Cell lines that have been tested so far are HT-29, LoVo, DLD-1, SW 1116 CaCo-2, RT-4.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsKRT20 / CK20 / Cytokeratin 20 Antibody (clone IT-Ks 20.10, FITC) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT20
Function Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
Cellular Location Cytoplasm
Tissue Location Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa
Research Areas
Citations (0)
citation

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Background

Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).

References

Moll R.,et al.Differentiation 53:75-93(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zhou Q.,et al.J. Biol. Chem. 281:16453-16461(2006).
Calnek D.,et al.Differentiation 53:95-104(1993).
Moll R.,et al.J. Cell Biol. 111:567-580(1990).

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$ 467.50
Cat# ALS14286
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