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SLC13A5 Antibody (clone 2G4)

Mouse Monoclonal Antibody

     
  • WB - SLC13A5 Antibody (clone 2G4) ALS14338
    SLC13A5 monoclonal antibody, clone 2G4. Western blot of SLC13A5 expression in HepG2.
  • IHC - SLC13A5 Antibody (clone 2G4) ALS14338
    Anti-SLC13A5 antibody IHC of human liver.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q86YT5
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2G4
Calculated MW 63kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 284111
Other Names Solute carrier family 13 member 5, Na(+)/citrate cotransporter, NaCT, Sodium-coupled citrate transporter, Sodium-dependent citrate transporter, SLC13A5, NACT
Target/Specificity Human SLC13A5
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsSLC13A5 Antibody (clone 2G4) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC13A5
Synonyms NACT
Function High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis
Research Areas
Citations (0)

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Background

High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.

References

Inoue K.,et al.Biochem. Biophys. Res. Commun. 299:465-471(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Chen R.,et al.J. Proteome Res. 8:651-661(2009).

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$ 450.00
Cat# ALS14338
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