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GSTA1 Antibody (clone 2F7)

Mouse Monoclonal Antibody

     
  • WB - GSTA1 Antibody (clone 2F7) ALS14378
    Western blot of GSTA1 expression in transfected 293T cell line by GSTA1 monoclonal antibody.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P08263
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2F7
Calculated MW 26kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 2938
Other Names Glutathione S-transferase A1, 2.5.1.18, GST HA subunit 1, GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, Glutathione S-transferase A1, N-terminally processed, GSTA1
Target/Specificity Human GSTA1
Reconstitution & Storage Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
PrecautionsGSTA1 Antibody (clone 2F7) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSTA1
Function Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene- 3,17-dione and may therefore play an important role in hormone biosynthesis (PubMed:11152686). Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)- hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid (PubMed:16624487).
Cellular Location Cytoplasm.
Tissue Location Liver.
Research Areas
Citations (0)
citation

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Background

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

References

Tu C.-P.D.,et al.Biochem. Biophys. Res. Commun. 141:229-237(1986).
Rhoads D.M.,et al.Biochem. Biophys. Res. Commun. 145:474-481(1987).
Tu C.-P.D.,et al.Biochem. Soc. Trans. 15:734-736(1987).
Board P.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:2377-2381(1987).
Rozen F.,et al.Arch. Biochem. Biophys. 292:589-593(1992).

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$ 533.50
Cat# ALS14378
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