|Application ||WB, IHC-P, IF, E|
|Dilution||ELISA (1:10000), IF (1:200-1:1000), IHC-P (1:200), WB (1:500-1:2000) ,|
|Other Names||Insulin gene enhancer protein ISL-1, Islet-1, ISL1|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ISLET-1 / ISL1 Antibody (clone 1H9) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity).|
|Tissue Location||Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain|
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Provided below are standard protocols that you may find useful for product applications.
Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity).
Wang M.,et al.Endocrinology 134:1416-1422(1994).
Tanizawa Y.,et al.Diabetes 43:935-941(1994).
Tanizawa Y.,et al.Diabetes 43:1171-1171(1994).
Zahedi R.P.,et al.J. Proteome Res. 7:526-534(2008).
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