STK17B / DRAK2 Antibody (clone 2C3)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | O94768 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2C3 |
Calculated MW | 42kDa |
Dilution | IF (10 µg/ml), IHC-P (3-5 µg/ml), WB (1:500-1:1000) |
Gene ID | 9262 |
---|---|
Other Names | Serine/threonine-protein kinase 17B, 2.7.11.1, DAP kinase-related apoptosis-inducing protein kinase 2, STK17B, DRAK2 |
Target/Specificity | Human DRAK2 |
Reconstitution & Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | STK17B / DRAK2 Antibody (clone 2C3) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STK17B |
---|---|
Synonyms | DRAK2 |
Function | Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis. |
Cellular Location | Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment. Note=Colocalizes with STK17B at the plasma membrane. |
Tissue Location | Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.
References
Sanjo H.,et al.J. Biol. Chem. 273:29066-29071(1998).
Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
Greenman C.,et al.Nature 446:153-158(2007).
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