|Application ||WB, IHC-P, IF, E|
|Dilution||IF (10 µg/ml), IHC-P (3-5 µg/ml), WB (1:500-1:1000)|
|Other Names||Serine/threonine-protein kinase 17B, 188.8.131.52, DAP kinase-related apoptosis-inducing protein kinase 2, STK17B, DRAK2|
|Reconstitution & Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||STK17B / DRAK2 Antibody (clone 2C3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.|
|Cellular Location||Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment. Note=Colocalizes with STK17B at the plasma membrane.|
|Tissue Location||Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.
Sanjo H.,et al.J. Biol. Chem. 273:29066-29071(1998).
Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
Greenman C.,et al.Nature 446:153-158(2007).
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