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PRDX5 / Peroxiredoxin 5 Antibody (clone 12A)

Mouse Monoclonal Antibody

     
  • WB - PRDX5 / Peroxiredoxin 5 Antibody (clone 12A) ALS14438
    0
    detail
  • IHC - PRDX5 / Peroxiredoxin 5 Antibody (clone 12A) ALS14438
    Anti-PRDX5 / Peroxiredoxin 5 antibody IHC of human lung, respiratory epithelium.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P30044
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Clone Names 12A
Calculated MW 22kDa
Dilution IHC-P (1:200), WB (1:2000),
Additional Information
Gene ID 25824
Other Names Peroxiredoxin-5, mitochondrial, 1.11.1.15, Alu corepressor 1, Antioxidant enzyme B166, AOEB166, Liver tissue 2D-page spot 71B, PLP, Peroxiredoxin V, Prx-V, Peroxisomal antioxidant enzyme, TPx type VI, Thioredoxin peroxidase PMP20, Thioredoxin reductase, PRDX5, ACR1
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsPRDX5 / Peroxiredoxin 5 Antibody (clone 12A) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRDX5 (HGNC:9355)
Synonyms ACR1
Function Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Cellular Location [Isoform Mitochondrial]: Mitochondrion
Tissue Location Widely expressed..
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Involved in intracellular redox signaling.

References

Kropotov A.,et al.Eur. J. Biochem. 260:336-346(1999).
Yamashita H.,et al.J. Biol. Chem. 274:29897-29904(1999).
Knoops B.,et al.J. Biol. Chem. 274:30451-30458(1999).
Zhou Y.,et al.Biochem. Biophys. Res. Commun. 268:921-927(2000).
Seo M.S.,et al.J. Biol. Chem. 275:20346-20354(2000).

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Discontinued
Cat# ALS14438
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