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ADK / Adenosine Kinase Antibody (clone AT4F8)

Mouse Monoclonal Antibody

     
  • WB - ADK / Adenosine Kinase Antibody (clone AT4F8) ALS14456
    Cell lysates (35 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with...
    detail
  • IHC - ADK / Adenosine Kinase Antibody (clone AT4F8) ALS14456
    Anti-ADK antibody IHC of human tonsil.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P55263
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names AT4F8
Calculated MW 41kDa
Dilution IHC-P (5 µg/ml), WB (1:1000),
Additional Information
Gene ID 132
Other Names Adenosine kinase, AK, 2.7.1.20, Adenosine 5'-phosphotransferase, ADK
Target/Specificity Human ADK
Reconstitution & Storage Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
PrecautionsADK / Adenosine Kinase Antibody (clone AT4F8) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADK (HGNC:257)
Function Catalyzes the phosphorylation of the purine nucleoside adenosine at the 5' position in an ATP-dependent manner. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
Cellular Location [Isoform 1]: Nucleus
Tissue Location Widely expressed. Highest level in placenta, liver, muscle and kidney.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.

References

Spychala J.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:1232-1237(1996).
Singh B.,et al.Eur. J. Biochem. 241:564-571(1996).
McNally T.,et al.Biochem. Biophys. Res. Commun. 231:645-650(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).

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Discontinued
Cat# ALS14456
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