|Application ||IHC-P, E, IE|
|Dilution||IHC-P (5 µg/ml)|
|Other Names||Coagulation factor IX, 188.8.131.52, Christmas factor, Plasma thromboplastin component, PTC, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain, F9|
|Target/Specificity||Recognizes human Factor IX as demonstrated by immunodiffusion. A single positive reactivity band was observed with Normal Human Plasma. No reaction was observed against F. IX-deficient plasma.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||F9 / Factor IX Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.|
|Tissue Location||Detected in blood plasma (at protein level) (PubMed:3857619, PubMed:8295821, PubMed:2592373, PubMed:9169594, PubMed:19846852). Synthesized primarily in the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
Kurachi K.,et al.Proc. Natl. Acad. Sci. U.S.A. 79:6461-6464(1982).
Jaye M.,et al.Nucleic Acids Res. 11:2325-2335(1983).
Anson D.S.,et al.EMBO J. 3:1053-1060(1984).
Yoshitake S.,et al.Biochemistry 24:3736-3750(1985).
McGraw R.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:2847-2851(1985).
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