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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Neurofibromin / NF1 Antibody (aa1551-1600)   

Neurofibromin / NF1 Antibody (aa1551-1600)

Rabbit Polyclonal Antibody

     
  • IF - Neurofibromin / NF1 Antibody (aa1551-1600) ALS14485
    Immunofluorescence of HepG2 cells, using NF1 Antibody.
  • WB - Neurofibromin / NF1 Antibody (aa1551-1600) ALS14485
    Western blot of extracts from HepG2 cells, using NF1 Antibody.
  • IHC - Neurofibromin / NF1 Antibody (aa1551-1600) ALS14485
    Anti-NF1 antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P21359
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 319kDa
Dilution ELISA (1:20000), IF (1:100-1:500), IHC-P (1:100), WB (1:500-1:1000) ,
Additional Information
Gene ID 4763
Other Names Neurofibromin, Neurofibromatosis-related protein NF-1, Neurofibromin truncated, NF1
Target/Specificity NF1 Antibody detects endogenous levels of total NF1 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsNeurofibromin / NF1 Antibody (aa1551-1600) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NF1
Function Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.
Cellular Location Nucleus. Nucleus, nucleolus
Tissue Location Detected in brain, peripheral nerve, lung, colon and muscle.
Volume 50 µl
Research Areas
Citations (0)

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Background

Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.

References

Bernards A.,et al.DNA Cell Biol. 11:727-734(1992).
Wallace M.R.,et al.Science 249:181-186(1990).
Wallace M.R.,et al.Science 250:1749-1749(1990).
Marchuk D.A.,et al.Genomics 11:931-940(1991).
Suzuki H.,et al.Biochem. Biophys. Res. Commun. 187:984-990(1992).

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$ 395.00
Cat# ALS14485
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