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GNAQ Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - GNAQ Antibody (Internal) ALS14487
    GNAQ antibody (0.1 ug/ml) staining of Rat Testis lysate (35 ug protein/ml in RIPA buffer).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P50148
Reactivity Human, Rat, Rabbit, Monkey, Pig, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 42kDa
Dilution ELISA (1:64000), IHC-P (5 µg/ml), WB (0.1-0.3 µg/ml)
Additional Information
Gene ID 2776
Other Names Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q, GNAQ, GAQ
Target/Specificity Human GNAQ.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsGNAQ Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GNAQ
Synonyms GAQ
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
Cellular Location Nucleus. Membrane. Nucleus membrane. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.
Tissue Location Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level).
Research Areas
Citations (0)

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Background

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).

References

Dong Q.,et al.Genomics 30:470-475(1995).
Chen B.,et al.Biochim. Biophys. Acta 1281:125-128(1996).
Johnson G.J.,et al.Biochem. J. 318:1023-1031(1996).
Gabbeta J.,et al.Thromb. Res. 91:29-32(1998).
Bai X.H.,et al.Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS14487
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