|Application ||WB, IHC-P, E|
|Dilution||IHC-P (5 µg/ml), WB (1:500-1:1000),|
|Other Names||Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Medium tumor antigen-associated 61 kDa protein, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha, PPP2R1A|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||PPP2R1A Antibody (clone 4E6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis.|
|Cellular Location||Cytoplasm. Chromosome, centromere. Note=Centromeric localization requires the presence of BUB1|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis.
Walter G.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:8669-8672(1989).
Hemmings B.A.,et al.Biochemistry 29:3166-3173(1990).
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (MAR-2007) to UniProtKB.
Zolnierowicz S.,et al.Biochem. J. 317:187-194(1996).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.