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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PPP2R1A Antibody (clone 4E6)   

PPP2R1A Antibody (clone 4E6)

Mouse Monoclonal Antibody

     
  • WB - PPP2R1A Antibody (clone 4E6) ALS14512
    PPP2R1A monoclonal antibody, clone 4E6. Western blot of PPP2R1A expression in Jurkat cell lysate.
  • IHC - PPP2R1A Antibody (clone 4E6) ALS14512
    Anti-PPP2R1A antibody IHC of human liver.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P30153
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4E6
Calculated MW 65kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 5518
Other Names Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Medium tumor antigen-associated 61 kDa protein, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha, PPP2R1A
Target/Specificity Human PPP2R1A
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsPPP2R1A Antibody (clone 4E6) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP2R1A
Function The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis.
Cellular Location Cytoplasm. Chromosome, centromere. Note=Centromeric localization requires the presence of BUB1
Research Areas
Citations (0)

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Background

The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis.

References

Walter G.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:8669-8672(1989).
Hemmings B.A.,et al.Biochemistry 29:3166-3173(1990).
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (MAR-2007) to UniProtKB.
Zolnierowicz S.,et al.Biochem. J. 317:187-194(1996).

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$ 450.00
Cat# ALS14512
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