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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   VAV2 Antibody (Internal)   

VAV2 Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - VAV2 Antibody (Internal) ALS14550
    Anti-VAV2 antibody IHC of human colon, submucosal plexus.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P52735
Reactivity Human, Mouse, Rat, Hamster, Monkey, Pig, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 101kDa
Dilution ELISA (1:32000), IHC-P (2.5-3.75 µg/ml), WB (1-1.5 µg/ml)
Additional Information
Gene ID 7410
Other Names Guanine nucleotide exchange factor VAV2, VAV-2, VAV2
Target/Specificity Human VAV2. This antobody is expected to recognise both reported isoforms (NP_001127870.1 and NP_003362.2).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsVAV2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VAV2
Function Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Background

Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).

References

Henske E.P.,et al.Ann. Hum. Genet. 59:25-37(1995).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mancini U.M.,et al.Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS14550
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