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STK26 / MST4 Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9P289 |
| Reactivity | Human, Mouse, Rat, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 47kDa |
| Dilution | ELISA (1:32000), IHC-P (2.5-3.75 µg/ml), WB (0.5-1.5 µg/ml) |
| Gene ID | 51765 |
|---|---|
| Other Names | Serine/threonine-protein kinase 26, 2.7.11.1, MST3 and SOK1-related kinase, Mammalian STE20-like protein kinase 4, MST-4, STE20-like kinase MST4, Serine/threonine-protein kinase MASK, STK26 (HGNC:18174) |
| Target/Specificity | Human MST4. This antibody is expected to recognize all three reported isoforms (NP_057626.2, NP_001035918.1 and NP_001035917.1). |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | STK26 / MST4 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STK26 (HGNC:18174) |
|---|---|
| Function | Serine/threonine-protein kinase that acts as a mediator of cell growth (PubMed:11641781, PubMed:17360971). Modulates apoptosis (PubMed:11641781, PubMed:17360971). In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006). Phosphorylates ATG4B at 'Ser- 383', thereby increasing autophagic flux (PubMed:29232556). |
| Cellular Location | Cytoplasm. Golgi apparatus Note=Colocalized with RIPOR1 in the Golgi of serum-starved cells and relocated to cytoplasmic punctae, probably vesicular compartments, along with RIPOR1 upon serum stimulation in a Rho- and PDCD10-dependent manner (PubMed:27807006). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Mediator of cell growth. Modulates apoptosis.
References
Lin J.-L.,et al.Oncogene 20:6559-6569(2001).
Qian Z.,et al.J. Biol. Chem. 276:22439-22445(2001).
Dan I.,et al.J. Biol. Chem. 277:5929-5939(2002).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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