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ELF1 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - ELF1 Antibody (C-Terminus) ALS14554
    Antibody staining (0.3 ug/ml) of Human Tonsil lysate (RIPA buffer, 35 ug total protein per lane).
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P32519
Reactivity Human, Rabbit
Host Goat
Clonality Polyclonal
Calculated MW 67kDa
Dilution ELISA (1:64000), IHC-P (2.5-3.75 µg/ml), WB (0.3-1 µg/ml)
Additional Information
Gene ID 1997
Other Names ETS-related transcription factor Elf-1, E74-like factor 1, ELF1
Target/Specificity Human ELF1. This antibody is expected to recognise both reported isoforms.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsELF1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELF1
Function Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.
Cellular Location Nucleus.
Tissue Location In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
Research Areas
Citations (0)

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Background

Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.

References

Leiden J.M.,et al.J. Virol. 66:5890-5897(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Thompson C.B.,et al.Mol. Cell. Biol. 12:1043-1053(1992).

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$ 395.00
Cat# ALS14554
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