|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:64000), IHC-P (2.5-3.75 µg/ml), WB (0.3-1 µg/ml)|
|Other Names||ETS-related transcription factor Elf-1, E74-like factor 1, ELF1|
|Target/Specificity||Human ELF1. This antibody is expected to recognise both reported isoforms.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||ELF1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.|
|Tissue Location||In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.|
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Provided below are standard protocols that you may find useful for product applications.
Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.
Leiden J.M.,et al.J. Virol. 66:5890-5897(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Thompson C.B.,et al.Mol. Cell. Biol. 12:1043-1053(1992).
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