|Application ||WB, IHC-P, IP|
|Dilution||IHC-P (10 µg/ml), IP (2 µg/ml), WB (2 µg/ml)|
|Other Names||Lymphocyte antigen 86, Ly-86, Protein MD-1, LY86, MD1|
|Target/Specificity||A KLH-conjugated synthetic peptide corresponding to amino acids 112-125 of human MD-1.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.|
|Precautions||MD-1 / LY86 Antibody (aa112-125) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).|
|Cellular Location||Secreted, extracellular space. Note=Associated with CD180 at the cell surface|
|Tissue Location||Highly expressed in B-cells, monocytes and tonsil|
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Provided below are standard protocols that you may find useful for product applications.
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).
Miura Y.,et al.Blood 92:2815-2822(1998).
Begum N.A.,et al.Biochem. Biophys. Res. Commun. 256:325-329(1999).
Mungall A.J.,et al.Nature 425:805-811(2003).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Ohto U.,et al.J. Mol. Biol. 413:815-825(2011).
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