SCNN1D Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | P51172 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 70kDa |
Dilution | ELISA (1:16000), IHC-P (2.5-3.75 µg/ml), |
Gene ID | 6339 |
---|---|
Other Names | Amiloride-sensitive sodium channel subunit delta, Delta-NaCH, Epithelial Na(+) channel subunit delta, Delta-ENaC, ENaCD, Nonvoltage-gated sodium channel 1 subunit delta, SCNED, SCNN1D, DNACH |
Target/Specificity | Human SCNN1D. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | SCNN1D Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SCNN1D |
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Synonyms | DNACH |
Function | Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
References
Waldmann R.,et al.J. Biol. Chem. 270:27411-27414(1995).
Ji H.L.,et al.J. Biol. Chem. 281:8233-8241(2006).
Bangel-Ruland N.,et al.Am. J. Respir. Cell Mol. Biol. 42:498-505(2010).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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