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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   PJA2 Antibody (aa141-190)   

PJA2 Antibody (aa141-190)

Rabbit Polyclonal Antibody

     
  • WB - PJA2 Antibody (aa141-190) ALS14624
    Western blot of extracts from Jurkat cells, using PJA2 Antibody.
  • IHC - PJA2 Antibody (aa141-190) ALS14624
    Anti-PJA2 antibody IHC of human kidney, glomeruli.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O43164
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 78kDa
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 9867
Other Names E3 ubiquitin-protein ligase Praja-2, Praja2, 6.3.2.-, RING finger protein 131, PJA2, KIAA0438, RNF131
Target/Specificity PJA2 Antibody detects endogenous levels of total PJA2 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsPJA2 Antibody (aa141-190) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PJA2
Synonyms KIAA0438, RNF131
Function Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes.
Cellular Location Cytoplasm. Cell membrane. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=Localizes at the cytoplasmic side of endoplasmic reticulum and Golgi apparatus Expressed in the postsynaptic density region of synapses (By similarity). Colocalizes with PRKAR2A and PRKAR2B in the cytoplasm and the cell membrane.
Volume 50 µl
Research Areas
Citations (0)

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Background

Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes.

References

Ishikawa K.,et al.DNA Res. 4:307-313(1997).
Nakajima D.,et al.Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS14624
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