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PROZ / Protein Z Antibody (clone 2B4)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P22891 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2B4 |
| Calculated MW | 45kDa |
| Dilution | ELISA (1:10000), IHC-P (1:200-1:400), WB (1:500-1:2000) |
| Gene ID | 8858 |
|---|---|
| Other Names | Vitamin K-dependent protein Z, PROZ |
| Target/Specificity | Human PROZ |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | PROZ / Protein Z Antibody (clone 2B4) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PROZ |
|---|---|
| Function | Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids. |
| Cellular Location | Secreted. |
| Tissue Location | Plasma. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.
References
Ichinose A.,et al.Biochem. Biophys. Res. Commun. 172:1139-1144(1990).
Fujimaki K.,et al.Biochemistry 37:6838-6846(1998).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Sejima H.,et al.Biochem. Biophys. Res. Commun. 171:661-668(1990).
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