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MUC16 / CA125 Antibody (aa13311-13360)

Rabbit Polyclonal Antibody

     
  • IF - MUC16 / CA125 Antibody (aa13311-13360) ALS14661
    Immunofluorescence of HepG2 cells, using MUC16 Antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IF, E
Primary Accession Q8WXI7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 2353kDa
Dilution ELISA (1:20000), IF (1:100-1:500), IHC-P (10 µg/ml)
Additional Information
Gene ID 94025
Other Names Mucin-16, MUC-16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125, MUC16, CA125
Target/Specificity MUC16 Antibody detects endogenous levels of total MUC16 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsMUC16 / CA125 Antibody (aa13311-13360) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MUC16 (HGNC:15582)
Function Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Cellular Location Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. Note=May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain
Tissue Location Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

References

O'Brien T.J.,et al.Tumor Biol. 23:154-169(2002).
O'Brien T.J.,et al.Tumor Biol. 22:348-366(2001).
Yin B.W.T.,et al.J. Biol. Chem. 276:27371-27375(2001).
Lloyd K.O.,et al.Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 467.50
Cat# ALS14661
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