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RNF144A / RNF144 Antibody (aa151-200)

Rabbit Polyclonal Antibody

     
  • WB - RNF144A / RNF144 Antibody (aa151-200) ALS14677
    Western blot of extracts from COLO cells, using RNF144A Antibody.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P50876
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 33kDa
Dilution ELISA (1:40000), IHC-P (1:100), WB (1:500-1:1000)
Additional Information
Gene ID 9781
Other Names E3 ubiquitin-protein ligase RNF144A, 6.3.2.-, RING finger protein 144A, UbcM4-interacting protein 4, Ubiquitin-conjugating enzyme 7-interacting protein 4, RNF144A, KIAA0161, RNF144, UBCE7IP4
Target/Specificity RNF144A Antibody detects endogenous levels of total RNF144A protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsRNF144A / RNF144 Antibody (aa151-200) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNF144A
Synonyms KIAA0161, RNF144, UBCE7IP4
Function E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.
Cellular Location Cell membrane; Single-pass membrane protein. Cytoplasmic vesicle membrane
Volume 50 µl
Research Areas
Citations (0)

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Background

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.

References

Nagase T.,et al.DNA Res. 3:17-24(1996).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Martinez-Noel G.,et al.FEBS Lett. 454:257-261(1999).
Ho S.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 111:E2646-E2655(2014).

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$ 395.00
Cat# ALS14677
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