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HnRNP-E1 / PCBP1 Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - HnRNP-E1 / PCBP1 Antibody (Internal) ALS14683
    PCBP1 antibody (0.01 ug/ml) staining of HeLa lysate (35 ug protein/ml in RIPA buffer).
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q15365
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 37kDa
Dilution ELISA (1:32000), IHC-P (5 µg/ml), WB (0.01-0.03 µg/ml)
Additional Information
Gene ID 5093
Other Names Poly(rC)-binding protein 1, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, hnRNP E1, Nucleic acid-binding protein SUB2.3, PCBP1
Target/Specificity Human PCBP1.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsHnRNP-E1 / PCBP1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PCBP1 {ECO:0000303|PubMed:7607214, ECO:0000312|HGNC:HGNC:8647}
Function Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (PubMed:7607214, PubMed:7556077, PubMed:8152927, PubMed:15731341). Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing (By similarity).
Cellular Location Nucleus. Cytoplasm. Note=Loosely bound in the nucleus (PubMed:7607214). May shuttle between the nucleus and the cytoplasm (PubMed:7607214).
Tissue Location Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands.
Research Areas
Citations (0)
citation

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Background

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.

References

Leffers H.,et al.Eur. J. Biochem. 230:447-453(1995).
Kiledjian M.,et al.EMBO J. 14:4357-4364(1995).
Aasheim H.-C.,et al.Nucleic Acids Res. 22:959-964(1994).
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Olsen J.V.,et al.Cell 127:635-648(2006).

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$ 467.50
Cat# ALS14683
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