|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:8000), IHC-P (5 µg/ml), WB (1-3 µg/ml)|
|Other Names||Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CDw217, CD217, IL17RA, IL17R|
|Target/Specificity||Mouse IL17RA / IL-17RA.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||IL17RA Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.|
|Cellular Location||Isoform 1: Membrane; Single- pass type I membrane protein|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for IL17A, IL17F and, in dimer with IL17RE, for IL17C. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
Yao Z.,et al.Cytokine 9:794-800(1997).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
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