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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   OXER1 Antibody   

OXER1 Antibody

Rabbit Polyclonal Antibody

     
  • WB - OXER1 Antibody ALS14693
    Western blot of OXER1 antibody ALS14693.
  • IHC - OXER1 Antibody ALS14693
    Anti-OXER1 antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q8TDS5
Reactivity Human, Mouse, Rat, Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 46kDa
Dilution IHC-P (5 µg/ml), WB (4 µg/ml),
Additional Information
Gene ID 165140
Other Names Oxoeicosanoid receptor 1, 5-oxo-ETE G-protein coupled receptor, G-protein coupled receptor 170, G-protein coupled receptor R527, G-protein coupled receptor TG1019, OXER1, GPR170, TG1019
Target/Specificity The high expression level of the receptor in leukocytes makes it the best positive control sample. When probing other tissue samples such as liver and kidney, membrane preparations or higher sensitivity detection systems may be required for visualiza ...
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsOXER1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OXER1
Synonyms GPR170, TG1019
Function Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages
Volume 1 ea
Research Areas
Citations (0)

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Background

Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.

References

Hosoi T.,et al.J. Biol. Chem. 277:31459-31465(2002).
Jones C.E.,et al.Mol. Pharmacol. 63:471-477(2003).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Takeda S.,et al.FEBS Lett. 520:97-101(2002).
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 395.00
Cat# ALS14693
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