|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat, Hamster|
|Dilution||IHC-P (10 µg/ml), WB (1:200),|
|Other Names||Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C, 126.96.36.199, PCK1, PEPCK1|
|Target/Specificity||Detects the protein at 63 kDa.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||PCK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|
|Tissue Location||Major sites of expression are liver, kidney and adipocytes|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
Stoffel M.,et al.Hum. Mol. Genet. 2:1-4(1993).
Ting C.-N.,et al.Genomics 16:698-706(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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