PLCG2 Antibody (aa721-770)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P16885 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 148kDa |
Dilution | ELISA (1:5000), IHC-P (10 µg/ml), WB (1:500-1:1000) |
Gene ID | 5336 |
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Other Names | 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-2, 3.1.4.11, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, PLC-IV, Phospholipase C-gamma-2, PLC-gamma-2, PLCG2 |
Target/Specificity | PLCG2 antibody detects endogenous levels of total PLCG2 protein. |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | PLCG2 Antibody (aa721-770) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PLCG2 (HGNC:9066) |
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Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling. |
Cellular Location | Membrane raft {ECO:0000250|UniProtKB:Q8CIH5}. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
References
Ohta S.,et al.FEBS Lett. 242:31-35(1988).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Kemmer D.,et al.BMC Genomics 7:48-48(2006).
Martin J.,et al.Nature 432:988-994(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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