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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KCNIP3 / Dream / Calsenilin Antibody (aa29-78)   

KCNIP3 / Dream / Calsenilin Antibody (aa29-78)

Rabbit Polyclonal Antibody

  • IF - KCNIP3 / Dream / Calsenilin Antibody (aa29-78) ALS14729
    Immunofluorescence of HeLa cells, using Calsenilin/KCNIP3 antibody.
  • WB - KCNIP3 / Dream / Calsenilin Antibody (aa29-78) ALS14729
    Western blot of extracts from MCF-7/Jurkat/A549 cells, using Calsenilin/KCNIP3 antibody.
  • IHC - KCNIP3 / Dream / Calsenilin Antibody (aa29-78) ALS14729
    Anti-KCNIP3 / CSEN antibody IHC of human brain, cortex neurons.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y2W7
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 29kDa
Dilution ELISA (1:20000), IF (1:100-1:500), IHC-P (10 µg/ml), WB (1:500-1:1000) ,
Additional Information
Gene ID 30818
Other Names Calsenilin, A-type potassium channel modulatory protein 3, DRE-antagonist modulator, DREAM, Kv channel-interacting protein 3, KChIP3, KCNIP3, CSEN, DREAM, KCHIP3
Target/Specificity Calsenilin/KCNIP3 antibody detects endogenous levels of total Calsenilin/KCNIP3 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsKCNIP3 / Dream / Calsenilin Antibody (aa29-78) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity).
Cellular Location Cytoplasm. Cell membrane; Lipid-anchor Endoplasmic reticulum. Golgi apparatus. Nucleus. Note=Also membrane-bound, associated with the plasma membrane (PubMed:15485870). In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus. {ECO:0000250, ECO:0000269|PubMed:15485870}
Tissue Location Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease
Volume 50 µl
Research Areas
Citations (0)

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Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation.


Buxbaum J.D.,et al.Nat. Med. 4:1177-1181(1998).
Carrion A.M.,et al.Nature 398:80-84(1999).
An W.F.,et al.Nature 403:553-556(2000).
Pruunsild P.,et al.Genomics 86:581-593(2005).
Isbrandt D.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS14729
(40 western blots)
Availability: 5 days
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