|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:1000), IHC-P (10 µg/ml), WB (1:500-1:1000)|
|Other Names||Solute carrier family 2, facilitated glucose transporter member 3, Glucose transporter type 3, brain, GLUT-3, SLC2A3, GLUT3|
|Target/Specificity||GLUT3 Antibody detects endogenous levels of total GLUT3 protein.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||SLC2A3 / GLUT3 Antibody (aa447-496) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane (PubMed:9477959, PubMed:26176916). Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate (PubMed:9477959, PubMed:26176916). Does not mediate fructose transport (PubMed:9477959, PubMed:26176916).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in brain. Expressed in many tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Facilitative glucose transporter. Probably a neuronal glucose transporter.
Kayano T.,et al.J. Biol. Chem. 263:15245-15248(1988).
Stuart C.A.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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