|Application ||WB, IHC-P, IF|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Axin-2, Axin-like protein, Axil, Axis inhibition protein 2, Conductin, AXIN2|
|Target/Specificity||Human AXIN2. AXIN2 antibody is predicted to not cross-react with AXIN2. At least four isoforms of AXIN2 are known to exist; this antibody will recognize all four.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||AXIN2 / Axin 2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity).|
|Tissue Location||Expressed in brain and lymphoblast.|
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Provided below are standard protocols that you may find useful for product applications.
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity).
Mai M.,et al.Genomics 55:341-344(1999).
Zhang T.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:1045-1049(2006).
Takahashi M.,et al.Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Liu W.,et al.Nat. Genet. 26:146-147(2000).
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