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HMMR / CD168 / RHAMM Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - HMMR / CD168 / RHAMM Antibody (N-Terminus) ALS14764
    Immunofluorescence of RHAMM in human stomach tissue with RHAM antibody at 20 ug/ml.
  • WB - HMMR / CD168 / RHAMM Antibody (N-Terminus) ALS14764
    Western blot analysis of RHAMM in rat stomach tissue lysate with RHAMM antibody at 1 ug/ml.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession O75330
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 84kDa
Dilution IHC-P (5 µg/ml), WB (0.5-1 µg/ml),
Additional Information
Gene ID 3161
Other Names Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168, HMMR, IHABP, RHAMM
Target/Specificity Human HMMR / RHAMM.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsHMMR / CD168 / RHAMM Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HMMR
Synonyms IHABP, RHAMM
Function Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity.
Cellular Location Cell surface. Cytoplasm.
Tissue Location Expressed in breast cancer cell lines and in normal breast tissue
Research Areas
Citations (0)

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Background

Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity.

References

Wang C.,et al.Gene 174:299-306(1996).
Assmann V.,et al.J. Cell Sci. 111:1685-1694(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS14764
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